D-para Hydroxy Phenyl Glycine (PHPG) CAS 22818-40-2

D-para Hydroxy Phenyl Glycine (PHPG) CAS 22818-40-2

PHPG is a medical intermediate which is mainly used in the synthesis or semi-synthetic of penicillin and cephalosporin. Because of its wide application and the synthetic medicinal products can be injected and taken orally, the clinical efficacy is better than Ampicillin.
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Product Details

Product name:              D-para Hydroxy Phenyl Glycine (PHPG)


Molecular Formula:      C8H9NO3


Molecular Structure:    



Molecular Weight:        167.162


CAS No.:                        22818-40-2



D-para Hydroxy Phenyl Glycine (PHPG) is a white crystal or white crystalline powder. It is slightly soluble in ethanol and water, easily soluble in acid or alkali solution to form salt.


D-para Hydroxy Phenyl Glycine (PHPG) is a kind of pharmaceutical fine chemicals. It is the side chain of synthetic β-lactams and semi-synthetic antibiotics. It is used in amoxicillin, cefoperazone, cefradine, ceftriaxine, ceftriaxone sodium and Hydroxy EPCP, 7ADCA. These drugs are widely used, both injectable and oral, they are broad-spectrum antibacterial and anti-inflammatory drugs, and have achieved satisfactory results in the clinical treatment of gastric and duodenal ulcers.



White crystal or crystalline powder.

Assay (HPLC)

≥ 98.5%

Water content (Loss on drying)

≤ 0.3%

Absorbance (5% in NaOH)

≤ 0.06

Absorbance (5% in HCl 410nm)

≤ 0.05

Specific Rotation (in HCl)

-156°to -161°

Fe Assay

≤10 ppm



25 kg/bucket

Storage   condition

Store in a cool and dry place.

Minimum Order

One package


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