Moxifloxacin Hydrochloride CAS 186826-86-8

Moxifloxacin Hydrochloride CAS 186826-86-8

Moxifloxacin hydrochloride is a fourth-generation extended-spectrum quinolone antibiotic, used in the treatment of community-acquired pneumonia, acute onset of chronic bronchitis, urinary tract infection, and acute sinusitis. The curative effect is remarkable and the adverse reaction is small.
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Product Details

Product name:      Moxifloxacin Hydrochloride

 

Molecular Formula:      CH25ClFN3O

 

Molecular Structure:    

                                      Molecular Structure                                             

Molecular Weight:    437.9


CAS No.:                   186826-86-8


Description

Moxifloxacin Hydrochloride is a light yellow or yellow powder or crystals, slightly hygroscopic. It is sparingly soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in acetone.


Application

Moxifloxacin Hydrochloride is a fluoroquinolone antibacterial drug. It can be used to treat socially acquired pneumonia caused by Staphylococcus aureus, influenza bacillus, pneumococcus, Moraxella catarrhalis, pneumoniae bacillus, etc., acute attack of chronic bronchitis, acute sinusitis, etc.


Specification

Appearance

Light yellow or yellow powder or crystals, slightly hygroscopic.


Solubility

Sparingly soluble in water, slightly soluble in ethanol (96 per   cent), practically insoluble in acetone.


Appearance of solution

The solution is not more opalescent than reference suspension II   and not more intensely colored than reference solution GY2


Identification A:

Positive by Specific optical rotation


Identification B:

The IR spectrum of sample should correspond to that of working   standard.


Identification C:

Reaction positive for chloride.


Assay

98.0~102.0% (C21H24FN3O4•HCl, anhydrous substance)


Related substances

Impurity A: ≤0.1%


Impurity B: ≤0.1%


Impurity C: ≤0.1%


Impurity D: ≤0.1%


Impurity E: ≤0.1%


Other maximum individual impurity: ≤0.1%


Total impurities: ≤0.3%


Specific optical rotation

-125°to -138°(20℃)


pH

3.9~4.6


Water

≤4.5%


Sulfated ash

≤0.1%


Heavy metal

≤10ppm


Residual solvents

Methanol: ≤0.3%


Ethanol: ≤0.5%


Acetonitrile: ≤0.041%


Dichloromethane: ≤0.06%


Tetrahydrofuran: ≤0.072%


Toluene: ≤0.089%


Microbiological Spec.

Total Aerobic Microbial Count: ≤1000 cfu/g


Total Yeast and Molds Count: ≤100 cfu/g





 

Packing          

20 KG/drum


Storage   condition:

Store in an airtight container, protected from light.


Minimum Order

One package

 

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