|Product name: ||Methyldopa|
Methyldopa is a white to yellowish-white, fine powder. It is soluble in dilute hydrochloric acid, the solubility in water at 25 ° C is about 10 mg / ml, the pH of the saturated aqueous solution is about 5. I t is slightly soluble in ethanol, insoluble in ether and chloroform.
Methyldopa is an α2-receptor agonistic cardiovascular drug. This product produces metabolite α-methylnorepinephrine in the body, which blocks central α receptors, thereby inhibiting the sympathetic impulse output of heart, kidney and peripheral blood vessels, at the same time, peripheral vascular resistance and plasma renin activity are also reduced, and blood pressure is therefore reduced. It can be used to treat hypertension, including hypertension in kidney disease. It is the first choice for the treatment of hypertension during pregnancy.
|Appearance ||White to yellowish-white, fine powder.|
|Identification A |
Infrared absorption: The sample comparing with the spectrum obtained with standard.
|Identification B |
HPLC: The retention time of the major peak the sample solution corresponds to that of the standard solution, as obtained in the Assay.
|Acidity (0.N NaOH)||≤0.50ml/g|
|Residue on ignition||≤0.1%|
|Impurity C ||≤0.15%|
|Assay（on dried basis）|
25kg/drum or as customer’s requirements.
Preserve in well-closed container.