| Product name: | Methyldopa |
| Molecular Formula: | C10H13NO4 |
| Molecular Structure: |  |
| Molecular Weight: | 211.214 |
| CAS No.: | 555-30-6 |
Description
Methyldopa is a white to yellowish-white, fine powder. It is soluble in dilute hydrochloric acid, the solubility in water at 25 ° C is about 10 mg / ml, the pH of the saturated aqueous solution is about 5. I t is slightly soluble in ethanol, insoluble in ether and chloroform.
Application
Methyldopa is mainly converted to methyl norepinephrine at the central. Methyl norepinephrine is a strong central alpha receptor agonist, for moderate, severe or malignant hypertension, as well as sedation and lowering intraocular pressure. It is especially suitable for high blood pressure with renal hypertension and renal dysfunction. This medicine mainly damages the cardiovascular system, liver, and blood system.
Specification
| Appearance | White to yellowish-white, fine powder. |
| Identification A | Infrared absorption: The sample comparing with the spectrum obtained with standard. |
| Identification B | HPLC: The retention time of the major peak the sample solution corresponds to that of the standard solution, as obtained in the Assay. |
| Specific rotation | -25°~-28° |
| Acidity (0.N NaOH) | ≤0.50ml/g |
| Water | 10.0~13.0% |
| Residue on ignition | ≤0.1% |
| Related compounds: | |
| 3-O-Methylmethyldopa | ≤0.15% |
| Impurity B | ≤0.15% |
| Impurity C | ≤0.15% |
| unspecified impurity | ≤0.05% |
| Total impurities | ≤0.5% |
| Residual solvents: | |
| Methanol | ≤3000ppm |
| Dichloromethane | ≤600ppm |
| Benzene | ≤2ppm |
| Toluene | ≤890ppm |
| Assay（on dried basis） | 98.0%～102.0% |
Packing
25kg/drum or as customer’s requirements.
Storage
Preserve in well-closed container.
Minimum Order
One package
![5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Ethyl Ester CAS 3543-74-6](/uploads/201920849/small/5-bis-2-hydroxyethyl-amino-1-methyl-1h07512815880.jpg)