|Product name: ||Clozapine|
|Molecular Formula:||C18H19ClN4 |
|Molecular Structure: |
|CAS No.: ||5786-21-0|
Clozapine is a yellow crystalline powder. It is soluble in chloroform, in acetone, and in alcohol; sparingly soluble in acetonitrile; insoluble in water.
Clozapine is an antipsychotic used to treat schizophrenia. Clozapine is a potent antagonist of dopamine and many other receptors, with a Ki value of 9.5 nM in combination with the M1 receptor.
|Appearance||Yellow crystalline powder.|
|Identification A||Infrared absorption: The IR spectrum of sample, exhibits maxima only at the same wavelength as that a similar preparation of USP|
Retention time by HPLC: The retention time of the major peak in the chromatogram of the Test solution corresponds to the major peak in the chromatogram of the Resolution solution.
|Loss on drying||≤0.5%|
|Residue on ignition|
|Impurity B ||≤0.2%|
|Individual unspecified impurity||≤0.10%|
|Total impurities ||≤0.6%|
|Assay（on dried basis）||98.0%～102.0%|
|Particle Size||90% pass 250um|
25kg/drum or as customer’s requirements.
Preserve in well-closed container.