Mometasone Furoate CAS 83919-23-7

Mometasone Furoate CAS 83919-23-7

Mometasone furoate is a new fluoride-free glucocorticoid derivative with high efficacy and few adverse reactions. It is suitable for use by the elderly, infants, and contact areas.
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Product Details

Product name:              Mometasone Furoate

 

Molecular Formula:      C27H30Cl2O6

 

Molecular Structure:    

                                      糠酸莫美他松结构图                                  

Molecular Weight:      615.5

CAS No.:                     83919-23-7


Description

Mometasone furoate is a white or almost white powder. It is practically insoluble in water, soluble in acetone and in methylene chloride, slightly soluble in ethanol (96 per cent).It melts at about 220 °C, with decomposition.


Application

Mometasone furoate is used for skin diseases that are effective in the treatment of corticosteroids, such as neurodermatitis, eczema, atopic dermatitis, etc. caused by skin inflammation and skin itching symptoms, topical moderate corticosteroids, anti-inflammatory and anti-inflammatory Itching and contraction of blood vessels. Used for patients with skin diseases, it can relieve inflammation and itching, especially in patients who respond to cortisone.


Specification

Appearance

White or almost white powder

Identification

Complies by IR

Complies by HPLC

Specific rotation

+56°to +62°

Loss on drying

Not more than 0.5%

Residue on ignition

Not more than 0.1%

Heavy metals

Not more than 30ppm

Related substances

Total impurities not more than 0.6%

Residue solvents

Methanol: Not more than 3000ppm

Acetone: Not more than 5000ppm

Dichloromethane: Not more than 600ppm

DMF: Not more than 880ppm

Assay (C27H30Cl2O6   calculated on the dried basis)

97.0 to 102.0%

 

Packing          

5kg/tin, 2tins/carton


Storage condition

Room temperature storage.


Minimum Order

One package

 

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