Hydrocortisone CAS 50-23-7

Hydrocortisone CAS 50-23-7

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Product Details

 

Product name: 
Hydrocortisone
Molecular Formula:
C21H30O5
Molecular Structure:
mtxx03
Molecular Weight:
362.5
CAS No.: 
50-23-7


Description

Hydrocortisone is a white or almost white, crystalline powder. It is practically insoluble in water, sparingly soluble in acetone and in ethanol (96 per cent), slightly soluble in methylene chloride. It shows polymorphism.

 

Application

Hydrocortisone can be used for diseases caused by adrenal insufficiency, rheumatoid arthritis, rheumatic fever, gout, bronchial asthma, etc. For allergic dermatitis, seborrheic dermatitis, pruritus, etc.

 

Specification

Appearance
White or almost white, crystalline powder.
Identification: 
a. Infrared absorption;

b. Retention time and size;

c. Thin-layer chromatography;

d. Fluorescence.
Specific optical rotation 
+162° to +168°
Loss on drying
≤1.0%
Related substances:

Each impurity (impurities C, D, E, I) 
≤0.5%
Impurity G  
≤0.4%
Impurity F  
≤0.3%
Each impurity (impurities A, B) 
≤0.2%
Each impurity (impurities H, N)
≤0.15%
Unspecified impurities≤0.10%
Total impurities
≤2.0%
Assay
97.0% - 103.0%

             

Packing and Storage

Preserve in well-closed containers. Store at 25°C, excursions permitted between 15°C and 30°C.

 

Minimum Order

One package

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