| Product name: | Hydrocortisone |
| Molecular Formula: | C21H30O5 |
| Molecular Structure: |  |
| Molecular Weight: | 362.5 |
| CAS No.: | 50-23-7 |
Description
Hydrocortisone is a white or almost white, crystalline powder. It is practically insoluble in water, sparingly soluble in acetone and in ethanol (96 per cent), slightly soluble in methylene chloride. It shows polymorphism.
Application
Hydrocortisone can be used for diseases caused by adrenal insufficiency, rheumatoid arthritis, rheumatic fever, gout, bronchial asthma, etc. For allergic dermatitis, seborrheic dermatitis, pruritus, etc.
Specification
| Appearance | White or almost white, crystalline powder. |
| Identification: | a. Infrared absorption; |
| b. Retention time and size; | |
| c. Thin-layer chromatography; | |
| d. Fluorescence. | |
| Specific optical rotation | +162° to +168° |
| Loss on drying | ≤1.0% |
| Related substances: | |
| Each impurity (impurities C, D, E, I) | ≤0.5% |
| Impurity G | ≤0.4% |
| Impurity F | ≤0.3% |
| Each impurity (impurities A, B) | ≤0.2% |
| Each impurity (impurities H, N) | ≤0.15% |
| Unspecified impurities | ≤0.10% |
| Total impurities | ≤2.0% |
| Assay | 97.0% - 103.0% |
Packing and Storage
Preserve in well-closed containers. Store at 25°C, excursions permitted between 15°C and 30°C.
Minimum Order
One package
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