Product name: Betadex sulfobutyl ether sodium, Injection grade
(β-Cyclodextrin, sulfobutyl ethers, sodium salts)
CAS No.: 182410-00-0
Molecular formula: C42H70-nO35 (C4H8O3S Na)n
Molecular weight: 1135+158n
Betadex sulfobutyl ether sodium is white to off-white, amorphous powder. Soluble in water, Insoluble in acetone, methanol, chloroform.
Betadex sulfobutyl ether sodium is a new type of pharmaceutical excipient, which belongs to a sulfonic derivative of anionic high water-soluble cyclodextrin. It can be well encapsulated with drug molecules to form non-covalent complexes, which improves the stability, water solubility, safety of the drug and effectively improves the biological activity of the drug molecule. It has low nephrotoxicity and can alleviate drug hemolysis Control the rate of drug release.
White to off-white, amorphous powder.
Freely soluble in water, sparingly soluble in methanol, practically insoluble in ethanol, in n-hexane, in 1-butanol, in acetonitrile, in 2-propanol and in ethyl acetate.
Same absorption bands as USP betadex sulfobutyl ether sodium RS.
The retention time of the major peak of sample solution corresponds to the standard solution.
Identification (Average Degree of Substitution)
Identify test are positive for Sodium
Bis(4-sulfobtyl) Ether Disodium
The total aerobic microbial count
The total combined moulds and yeasts count
Clarity of Solution
30%(w/v) solution is clear and essentially free from particles of foreign matter.
Average Degree of Substitution
Peaks I-X (%peak area):
500g/bag , 1kg/bag , 2kg/bag, 10kg/drum.
Preserve in well-closed containers, and store at room temperature. Protect from moisture.