Timolol Maleate CAS 26921-17-5

Timolol Maleate CAS 26921-17-5

Product name: Timolol Maleate CAS No.: 26921-17-5
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Product Details


Product name:      Timolol Maleate

 

Molecular Formula:      C17H28N4O7S

 

Molecular Structure:    

                                      Molecular Structure 

Molecular Weight:       432.49

CAS No.:                      26921-17-5


Description

Timolol Maleate is white or almost white, crystalline powder or colorless crystals.


Application

Timolol Maleate is a new potent β-receptor blocker, which is clinically used to treat hypertension, angina pectoris, tachycardia and glaucoma.

1. It is used for essential hypertension, has a good effect on mild and moderate hypertension, and can be used in combination with diuretics;

2. For coronary heart disease, it can be used for the treatment of angina pectoris and myocardial infarction;

3. Used for tachycardia;

4. Prevent migraine;

5. The eye drops of this medicine are used for the treatment of glaucoma, especially for primary, open-angle glaucoma, and have the effect of traditional traditional eye pressure lowering drugs. It can also be used for angle-closure glaucoma implants, aphakic glaucoma, some people with secondary glaucoma, ocular hypertension, and glaucoma that is ineffective to drugs and surgery. Can be combined with miotic drugs.

 

Specification

Appearance

White or almost white, crystalline powder or colorless crystals.

Solubility

Soluble in water and in ethanol (96 percent)

Melting point

199℃ ~ 203℃

Identification (IR)

IR spectrum of sample corresponds to the IR spectrum of   reference standard.

Identification (Specific optical rotation)

-5.7°to -6.2°

Solution color and clarity

Solution is clear and not more intensely colored than reference   solution B8

PH value

3.8~4.3

R-isomer content

≤1.0%

Related substances:


Impurity B

≤0.2%

Impurity C

≤0.2%

Impurity D

≤0.2%

Impurity E

≤0.2%

Impurity F

≤0.2%

Single unknown impurity

≤0.10%

Total impurities

≤0.4%

Loss on drying

≤0.5%

Residue on ignition

≤0.1%

Assay (dried substance)

98.5%~101.0%

 

Packing          

20 kg/bucket

Storage   condition:

Room temperature storage.

Minimum Order

One package

 

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