Ramipril CAS 87333-19-5

Ramipril CAS 87333-19-5

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Product Details

 

Product name: 
Ramipril
Molecular Formula:
C23H32N2O5
Molecular Structure:
mtxx90
Molecular Weight:   
416.5
CAS No.:
87333-19-5


Description

Ramipril is a white or almost white, crystalline powder. It is sparingly soluble in water, freely soluble in methanol.

 

Application

Ramipril is a new second generation angiotensin converting enzyme inhibitor. It is a powerful and durable vasodilator. It is suitable for:

1) Essential hypertension

2) Congestive heart failure

3) Mild to moderate heart failure after acute myocardial infarction

 

Specification

Appearance 
White or almost white, crystalline powder.
Identification
a. Specific optical rotation;

b. Infrared absorption.
Appearance of solution
Meets the requirements.
Melting range
105°C to 112°C
Specific optical rotation
+ 32.0° to + 38.0°
Palladium
≤20 ppm
Loss on drying  
≤0.2%
Sulfated ash
≤0.1%
Related substances:

Ramipril methylester
≤0.5%
Ramipril isopropyl ester  
≤0.5%
Hexahydroramipril
≤0.5%
Ramipril diketopiperazine    
≤0.5%
Unspecified impurities  
≤0.10%
Total impurities   
≤1.0%
Assay
98.0%-101.0%


Packing and Storage

Preserve in tight containers.

 

Minimum Order

One package

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