Pravastatin Sodium CAS 81131-70-6

Pravastatin Sodium CAS 81131-70-6

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Product Details

 

Product name: 
Pravastatin Sodium
Molecular Formula: 
C23H35NaO7
Molecular Structure:
mtxx88
Molecular Weight:
446.5
CAS No.:  
81131-70-6


Description

Pravastatin sodium is a white or yellowish-white powder or crystalline powder. It is freely soluble in water and in methanol, soluble in anhydrous ethanol.

 

Application

Pravastatin sodium is mainly used for primary hypercholesterolemia (IIa and IIb hyperlipidemia) that cannot be controlled by dietary restriction.

 

Specification

Appearance

White or yellowish-white powder or crystalline powder, hygroscopic.

Appearance of solution
Meets the requirements.
PH   
7.2 - 9.0
Specific optical rotation  
+ 153° to + 159°
Ethanol
≤3.0%
Heavy metals
≤20 ppm
Water 
≤4.0%
Related substances:

6′-epipravastatin
≤0.3%
3’’-(R)-hydroxypravastatin
≤0.2%

(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[[(2S)-2-methylpentanoyl]oxy]- 1,2,6,7,8,8ahexahydronaphthalen-1-yl]heptanoic acid

≤0.2%
Pravastatin lactone 
≤0.2%
3’’-(S)-hydroxypravastatin
≤0.2%

( 3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5- dihydroxyheptanoic acid

≤0.15%
(3R,5R)-3,5-dihydroxy-7-[(1S,2S)-6-hydroxy-2-methyl-1,2-dihydronaphthalen-1-yl]heptanoic acid 
≤0.15%
Unspecified impurities
≤0.10%
Total impurities
≤0.6%
Assay 97.0%-102.0%


Packing and Storage

Preserve in tight containers. Store as per labeling instructions.

 

Minimum Order

One package

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