Nimodipine CAS 66085-59-4

Nimodipine CAS 66085-59-4

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Product Details


Product name: 
Nimodipine
Molecular Formula:
C21H26N2O7
Molecular Structure:
mtxx87
Molecular Weight:
418.4
CAS No.:
66085-59-4


Description

Nimodipine is a light yellow or yellow, crystalline powder. It is practically insoluble in water, freely soluble in ethyl acetate, sparingly soluble in anhydrous ethanol. It shows polymorphism.

 

Application

Nimodipine is used for the improvement of blood circulation during the recovery period of acute cerebrovascular disease, and cerebral vasospasm after subarachnoid hemorrhage for various reasons. Also used as a treatment for ischemic neuronal protection and vascular dementia.

 

Specification

Appearance
Light yellow or yellow, crystalline powder.
Appearance of solution
Meets the requirements.
Optical rotation
-0.10° to +0.10°
Loss on drying
≤0.5%
Sulfated ash
≤0.1%
Related substances:

2-methoxyethyl 1-methylethyl 2,6-dimethyl-4-(3-nitrophenyl) pyridine-3, 5-dicarboxylate
≤0.1%
Bis(1-methylethyl) 2,6-dimethyl-4- (3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
≤0.2%
Bis(2-methoxyethyl) 2,6-dimethyl -4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
≤0.2%
Total impurities
≤0.5%
Assay
98.5%-101.5%


Packing and Storage

Preserve in tight, light-resistant containers, and store at 25°C, excursions permitted between 15°C and 30°C.

 

Minimum Order

One package

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