D-Mannitol CAS 69-65-8

D-Mannitol CAS 69-65-8

D-mannitol is mainly used as a raw material in the pharmaceutical industry for the preparation of diuretics, dehydrating agents, disaccharide substitutes, pharmaceutical excipients and the like. It can also be used as a sweetener, anti-adhesive agent, nutritional supplement, quality improver and moisturizer in the food industry.
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Product Details


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D-Mannitol occurs as a white, crystalline powder or as free flowing granules consisting of D-mannitol and a small quantity of sorbitol. It is soluble in water and in pyridine, very slightly soluble in alcohol, and practically insoluble in chloroform and ether.



Mannitol is a good diuretic in medicine, reducing intracranial pressure, intraocular pressure and treating kidney drugs, dehydrating agents, sugar substitutes, and also used as an excipient for tablets and a solid and liquid diluent. As a hyperosmotic antihypertensive drug, mannitol injection is a commonly used drug for clinical rescue, especially for the rescue of brain diseases. It has the characteristics of rapid blood pressure lowering and accurate curative effect required by drugs for reducing intracranial pressure. As an excipient for tablets, mannitol is non-hygroscopic, dries quickly, has good chemical stability, and has the characteristics of refreshing and good granulation properties. In addition, it is also used in chewable tablets such as sobering medicine and mouth cooling agent. In terms of food, the product has the least water absorption among sugars and sugar alcohols, and has a refreshing sweetness. It is used for anti-sticking in foods such as maltose, chewing gum, and rice cakes, and as anti-sticking powder for general pastries. It can also be used as a low-calorie and low-sugar sweetener such as food for diabetic patients and bodybuilding food. Although mannitol can be absorbed by the human gastrointestinal tract, it does not accumulate in the body.



White or almost white crystalline powder or free-flowing granules
Appearance of solution
Clear and colourless
≤ 20µS•cm-1
Reducing sugars
≤ 0.2%
Related substances:

≤ 2.0%
≤ 2.0%
≤ 2.0%
Any unspecified impurity
≤ 0.10%
Total impurities
≤ 2.0%
≤ 0.5ppm
≤ 1ppm
≤ 0.5%
Bacterial endotoxins (for parenteral preparations)
<4IU/g (concentration <100g/L)

<2.5IU/g (concentration ≥100g/L)
Microbial contamination (for parenteral preparations)
TAMC: ≤ 100CFU/g
Microbial contamination (not for parenteral preparations)
TAMC: ≤ 1000CFU/g

TYMC: ≤ 100CFU/g

Escherichia coli: absent

Salmonella: absent


25kg/ bag or as per requirement



Store in a cool dry place


Minimum Order

One package

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