Captopril CAS 62571-86-2

Captopril CAS 62571-86-2

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Product Details

 

Product name: 
Captopril
Molecular Formula:
C9H15NO3S
Molecular Structure:
mtxx76
Molecular Weight: 
217.3
CAS No.: 
62571-86-2


Description

Captopril is a white or almost white, crystalline powder. It is soluble in water, freely soluble in methanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.

 

Application

Captopril is used in the treatment of various types of hypertension, especially in the treatment of intractable hypertension that is ineffective against other antihypertensive drugs. Also used for acute and chronic congestive heart failure, better combined with cardiotonic or diuretic.

 

Specification

Appearance 
White or almost white, crystalline powder.
Appearance of solution
Meets the requirements.
PH
2.0 - 2.6
Specific optical rotation
−127° to −132°
epi-captopril
≤0.2%
Heavy metals
≤20 ppm
Loss on drying ≤1.0%
Sulfated ash ≤0.2%
Related substances:

Captopril disulfide
≤1.0%
(2S)-1-[(2S)-3-bromo-2-methylpropanoyl]-pyrrolidine-2-carboxylic acid
≤0.15%
(2S)-1-(2-methylpropanoyl)pyrrolidine-2-carboxylic acid
≤0.15%
(2RS)-2-methyl-3-sulfanylpropanoic acid 
≤0.15%
(2RS)-3-bromo-2-methylpropanoic acid
≤0.15%
Acetylcaptopril
≤0.2%
Unspecified impurities
≤0.10%
Total impuritie
≤1.2%
Assay
98.0%-101.5%


Packing and Storage

Preserve in tight container.

 

Minimum Order

One package

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