Candesartan Cilexetil CAS 145040-37-5

Candesartan Cilexetil CAS 145040-37-5

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Product Details

 

Product name:
Candesartan Cilexetil
Molecular Formula:
C33H34N6O6
Molecular Structure:
mtxx75
Molecular Weight
610.660
CAS No.:  
145040-37-5


Description  

Candesartan Cilexetil is a white to off-white powder. It is practically insoluble in water, sparingly soluble in methanol.

 

Application

Candesartan is a prodrug of candesartan, the intensity of action is 10 times that of losartan, the selectivity of action is good, the duration of action is long, due to the release of the activity of the prodrug after oral administration is relatively mild, Therefore, it is an ideal treatment for hypertension.

 

Specification

Appearance 
White to off-white powder.
Identification
(1) IR spectrum should be identical to that of candesartan cliexetil standard.

(2) The retention time of the major peak of the sample solurion corresponds to that of the standard solution.

Water (KF)
≤0.3%
Residue on ignition 
≤0.1%
Ca
3.0~3.6%
Related compounds:

Ethyl candesartan
≤0.2%
Desethyl candesartan cliexetil
≤0.3%
N-2’-ethyl candesartan cliexetil
≤0.2%
Any other individual impurity
≤0.10%
Total impurity
≤0.6%
Assay(on anhydrous basis)
98.7%~101.0% of C33H34N6O6

Residual solvents(GC):


Acetone
≤5000ppm
Methanol 
≤3000ppm
Ethanol
≤5000ppm
Methylene chloride
≤600ppm
Diethyl ether   
≤5000ppm
Ethyl acetate
≤5000ppm
N,N-Dimethylformamide
≤880ppm


Packing

25kg/ bag or as customer’s requirements.

 

Storage

Preserve in well-closed container.

 

Minimum Order

One package

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