Allopurinol CAS 315-30-0

Allopurinol CAS 315-30-0

Allopurinol and its metabolites can inhibit xanthine oxidase, so that hypoxanthine and xanthine cannot be converted into uric acid, that is, the synthesis of uric acid is reduced, thereby reducing the concentration of uric acid in the blood, and reducing the amount of urate in bones, joints and kidneys. Composure, a drug that can inhibit the synthesis of uric acid. This product can inhibit the activity of liver drug enzymes.
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Product Details

 

Product name:
Allopurinol
Molecular Formula: 
C5H4N4O
Molecular Structure:
mtxx28
Molecular Weight: 
136.1
CAS No.:
315-30-0


Description

Allopurinol is a white or almost white powder. It is very slightly soluble in water and in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides.

 

Application

Allopurinol is an anti-gout drug. It is suitable for various diseases such as gout, acute or chronic leukemia, which are primary or secondary serum uric acid.

 

Specification

Appearance
White or almost white powder.
Heavy metals
≤20 ppm
Loss on drying
≤0.5%
Sulfated ash
≤0.1%
Related substances:

5-amino-1H-pyrazole-4-carboxamide
≤0.2%
5-(formylamino)-1H-pyrazole-4-carboxamide
≤0.1%
5-(4H-1,2,4-triazol-4-yl)-1H-pyrazole-4-carboxamide
≤0.1%

Sum of impurities other than 5- amino-1H-pyrazole-4-carboxamide,5-(formylamino)-1H-pyrazole-4-

carboxamide and 5-(4H-1,2,4- triazol-4-yl)-1H-pyrazole-4-carboxamide

≤0.3%
Ethyl 5-amino-1H-pyrazole-4- carboxylate  
≤0.1%
Ethyl 5-(formylamino)-1Hpyrazole -4-carboxylate
≤0.1%
Hydrazine
10 ppm of hydrazine sulfate

Equivalent to 2.5 ppm of hydrazine
Assay
97.0%-102.0%


Packing and Storage

Preserve in well-closed containers. Store at room temperature.

 

Minimum Order

One package

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