Etoposide CAS 33419-42-0

Etoposide CAS 33419-42-0

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Product Details

 

Product name: 
Etoposide
Molecular Formula: 
C29H32O13
Molecular Structure:
mtxx27
Molecular Weight:
588.6
CAS No.:
33419-42-0


Description

Etoposide is a semisynthetic derivative of podophyllotoxin used in the treatment of certain neoplastic diseases. It is very soluble in methanol and chloroform, slightly soluble in ethanol, and sparingly soluble in water and ether.

 

Application

Etoposide is a cell cycle specific antitumor drug. It is mainly used for the treatment of small cell lung cancer, and is also effective for acute leukemia, malignant lymphoma, testicular tumor, bladder cancer, prostate cancer, gastric cancer, chorionic epithelial cancer, ovarian cancer, malignant mole.

 

Specification

Appearance
White or almost white, crystalline powder, slightly hygroscopic.
Appearance of solution
Meets the requirements
Specific optical rotation 
-106° to -114°
Heavy metals
≤20 ppm
Water 
≤6.0%
Sulfated ash 
≤0.1%
Related substances:

Cis-etoposide
≤0.2%
α-etoposide
≤0.2%
Lignan P 
≤0.2%
4′-desmethylepipodophyllotoxin
≤0.2%
Impurities N  
≤0.2%
Impurities O
≤0.15%
Unspecified impurities
≤0.1%
Total impurities
 ≤1.0%
Assay
98.0%-101.0%


Packing and Storage

Preserve in tight, light-resistant container.

 

Minimum Order

One package

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