Azathioprine CAS 446-86-6

Azathioprine CAS 446-86-6

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Product Details

 

Product name: 
Azathioprine
Molecular Formula: 
C9H7N7O2S
Molecular Structure:
mtxx22
Molecular Weight:
277.26
CAS No.: 
446-86-6


Description

Azathioprine is insoluble in water, but may be dissolved with addition of one molar equivalent of alkali. It is stable in solution at neutral or acid pH but hydrolysis to mercaptopurine occurs in excess sodium hydroxide (0.1N), especially on warming.

 

Application

Azathioprine is mainly used for anti-rejection reactions during organ transplantation, and is often used in combination with corticosteroids or anti-lymphocyte globulin. It is also widely used in autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, active chronic hepatitis, ulcerative colitis, myasthenia gravis, and scleroderma.

 

Specification

Appearance
Pale-yellow powder
Loss on drying 
≤1.0%
Sulfated ash
≤0.1%
Related substances:

1-methyl-4-nitro-1H-imidazol-5- amine
≤0.15%
Mercaptopurine
≤0.15%
Unspecified impurities  
≤0.10%
Total impurities
≤0.5%
Assay 
98.5%-101.0%


Packing and Storage

Preserve in tight, light-resistant containers.

 

Minimum Order

One package

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