| Product name: | Azathioprine |
| Molecular Formula: | C9H7N7O2S |
| Molecular Structure: |  |
| Molecular Weight: | 277.26 |
| CAS No.: | 446-86-6 |
Description
Azathioprine is insoluble in water, but may be dissolved with addition of one molar equivalent of alkali. It is stable in solution at neutral or acid pH but hydrolysis to mercaptopurine occurs in excess sodium hydroxide (0.1N), especially on warming.
Application
Azathioprine is mainly used for anti-rejection reactions during organ transplantation, and is often used in combination with corticosteroids or anti-lymphocyte globulin. It is also widely used in autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, active chronic hepatitis, ulcerative colitis, myasthenia gravis, and scleroderma.
Specification
| Appearance | Pale-yellow powder |
| Loss on drying | ≤1.0% |
| Sulfated ash | ≤0.1% |
| Related substances: | |
| 1-methyl-4-nitro-1H-imidazol-5- amine | ≤0.15% |
| Mercaptopurine | ≤0.15% |
| Unspecified impurities | ≤0.10% |
| Total impurities | ≤0.5% |
| Assay | 98.5%-101.0% |
Packing and Storage
Preserve in tight, light-resistant containers.
Minimum Order
One package
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