Doxycycline Monohydrate CAS 17086-28-1

Doxycycline Monohydrate CAS 17086-28-1

Doxycycline monohydrate is an anti-infective drug. Its fat solubility is 5 times larger than tetracycline and 50 times larger than oxytetracycline. The antibacterial spectrum is the same as tetracycline, but the effect is 2-10 times stronger than the latter. It is still effective against Staphylococcus aureus resistant to tetracycline. The clinical use is the same as tetracycline.
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Product Details

 

Product name:  
Doxycycline Monohydrate
Molecular Formula
C22H24N2O8,H2O
Molecular Structure 
mtxx08
Molecular Weight
462.5
CAS No.: 
17086-28-1  


Description

Doxycycline Monohydrate is a yellow, crystalline powder. It is very slightly soluble in water and in alcohol. It dissolves in dilute solutions of mineral acids and in solutions of alkali hydroxides and carbonates.

 

Application

Doxycycline Monohydrate is mainly used for upper respiratory tract infection, tonsillitis, biliary tract infection, lymphadenitis, cellulitis, chronic bronchitis in the elderly caused by sensitive Gram-positive cocci and Gram-negative bacilli. Also used for typhus, ascariasis, mycoplasmal pneumonia. It can also be used to treat cholera and also to prevent falciparum malaria and leptospirosis infection.

 

Specification

Appearance
Yellow, crystalline powder.
PH5.0 - 6.5
Specific optical rotation 
- 113° to - 130°
Specific absorbance
325 - 363
Light-absorbing impurities
Meets the requirements.
Heavy metals  
≤50 ppm
Water
3.6% - 4.6%
Sulfated ash 
≤0.4%
Related substances:

6-epidoxycycline
≤2.0%
Metacycline
≤2.0%
Any other impurity
≤0.5%
Assay

95.0%-102.0%



Packing and Storage

Preserve in tight, light-resistant container.

 

Minimum Order

One package

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