Doxycycline Hyclate CAS 24390-14-5

Doxycycline Hyclate CAS 24390-14-5

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Product Details


Product name:  
Doxycycline Hyclate
Molecular Formula
C22H24N2O8,HCI,½C2H6O,½H2O
Molecular Structure
mtxx07
Molecular Weight
512.9
CAS No.:  
24390-14-5


Description

Doxycycline hyclate is a yellow, hygroscopic, crystalline powder. It is freely soluble in water and in methanol, sparingly soluble in ethanol (96 per cent). It dissolves in solutions of alkali hydroxides and carbonates.

 

Application

Doxycycline hyclate is a tetracycline antibiotic. It is mainly used for upper respiratory tract infection, tonsillitis, biliary tract infection, lymphadenitis, cellulitis, senile chronic bronchitis caused by sensitive gram-positive cocci and gram-negative bacilli. It is also used for typhus, tsutsugamushi disease and Mycoplasma pneumonia. It can also be used to treat cholera and to prevent falciparum malaria and Leptospira infection.

 

Specification

Appearance
Yellow, hygroscopic, crystalline powder.
PH
2.0 - 3.0
Specific optical rotation
-120° to -105°
Specific absorbance
300 - 335
Light-absorbing impurities
Meets the requirements.
Ethanol   
4.3% - 6.0%
Heavy metals
≤50 ppm 
Water   
1.4% - 2.8%
Sulfated ash
≤0.4%
Bacterial endotoxins
≤1.14 IU/mg
Related substances:

6-epidoxycycline
≤2.0%
Metacycline
≤2.0%
4-epidoxycycline
≤0.5%
4-epi-6-epidoxycycline
≤0.5%
oxytetracycline
≤0.5%

( 4S,4aR,5S,5aR,6R,12aS)-2-acetyl-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-4a,

5a,6,12atetrahydrotetracene-1,11(4H,5H)-dione (2-acetyl-2- decarbamoyldoxycycline)              

≤0.5%
Any other impurity
≤0.5%
Assay

95.0%-102.0%

        

Packing and Storage

Preserve in an airtight container, protected from light. If the substance is sterile, store in a sterile, airtight, tamper-proof container.

 

Minimum Order

One package

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